Software
Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes
Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes
Kunhee Kim, Hyungryul Baik, Chloe Soohyun Jang, Jin Kyung Roh, Eleazer Eskin, Buhm Han. “Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes” Genome Biology (2019) 20:175
Keyword : #privacy, #genetic_distance
Kunhee Kim, Hyungryul Baik, Chloe Soohyun Jang, Jin Kyung Roh, Eleazer Eskin, Buhm Han. “Genomic GPS: using genetic distance from individuals to public data for genomic analysis without disclosing personal genomes” Genome Biology (2019) 20:175
Keyword : #privacy, #genetic_distance
MergeReference merges multiple reference panels for HLA imputation. The merged reference panel could be used for running CookHLA and SNP2HLA.
MergeReference merges multiple reference panels for HLA imputation. The merged reference panel could be used for running CookHLA and SNP2HLA.
Cook, Seungho, and Buhm Han. “MergeReference: a tool for merging reference panels for HLA imputation.” Genomics & Informatics 15, no. 3 (2017): 108.
Keyword : #HLA, #imputation, #mergereference
Cook, Seungho, and Buhm Han. “MergeReference: a tool for merging reference panels for HLA imputation.” Genomics & Informatics 15, no. 3 (2017): 108.
Keyword : #HLA, #imputation, #mergereference
FOLD is to obtain a set of summary statistics from each study, where each statistic is calculated using a subset of controls that is homogeneous in terms of their information.
FOLD is to obtain a set of summary statistics from each study, where each statistic is calculated using a subset of controls that is homogeneous in terms of their information.
Eunji Kim, Buhm Han, “A power-preserving meta-analysis framework for overlapping samples”, Bioinformatics. 33(24):3947-3954. 2017
Keyword : #meta_analysis, #fixed_effect
Eunji Kim, Buhm Han, “A power-preserving meta-analysis framework for overlapping samples”, Bioinformatics. 33(24):3947-3954. 2017
Keyword : #meta_analysis, #fixed_effect
RE2C is an extended version of the Random Effect model 2 (RE2) implemented in METASOFT
RE2C is an extended version of the Random Effect model 2 (RE2) implemented in METASOFT
Cue. H. Lee, Eleazar. Eskin., Buhm Han. “Increasing power of meta-analysis of genome-wide association studies for detecting heterogeneous effects”, Bioinformatics, vol. 33, no. 14m pp. i-379-i388, 2017.
Keyword : #meta_analysis, #random_effect
Cue. H. Lee, Eleazar. Eskin., Buhm Han. “Increasing power of meta-analysis of genome-wide association studies for detecting heterogeneous effects”, Bioinformatics, vol. 33, no. 14m pp. i-379-i388, 2017.
Keyword : #meta_analysis, #random_effect
BUHMBOX is a tool to distinguish pleiotropy and clinical heterogeneity.
BUHMBOX is a tool to distinguish pleiotropy and clinical heterogeneity.
Buhm Han, Jennie G Pouget, Kamil Slowikowski, Eli Stahl, Cue Hyunkyu Lee, Dorothee Diogo, Xinli Hu, Yu Rang Park, Eunji Kim, Peter K Gregersen, Solbritt Rantapaa Dahqvist, Jane Worthington, Steve Eyre, Lars Klareskog, Tom Huizinga, Wei-Min Chen, Suna Onengut-Gumuscu, Stephen S Rich, Major Depressive Disorder Working Group of the PGC, Naomi Wray, Soumya Raychaudhuri “A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.” Nature Genetics. 48(7):803-10. 2016
Keyword: #pleiotropy, #heterogeneity, #ng
Buhm Han, Jennie G Pouget, Kamil Slowikowski, Eli Stahl, Cue Hyunkyu Lee, Dorothee Diogo, Xinli Hu, Yu Rang Park, Eunji Kim, Peter K Gregersen, Solbritt Rantapaa Dahqvist, Jane Worthington, Steve Eyre, Lars Klareskog, Tom Huizinga, Wei-Min Chen, Suna Onengut-Gumuscu, Stephen S Rich, Major Depressive Disorder Working Group of the PGC, Naomi Wray, Soumya Raychaudhuri “A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.” Nature Genetics. 48(7):803-10. 2016
Keyword: #pleiotropy, #heterogeneity, #ng
SNP2HLA imputes HLA genes and amino acids from SNP genotype data.
SNP2HLA imputes HLA genes and amino acids from SNP genotype data.
Xiaoming Jia, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J. Concannon, Stephen S. Rich, Soumya Raychaudhuri, Paul I.W. de Bakker. “ Imputing Amino Acid Polymorphisms in Human Leukocyte Antigenes. ” PLoS One. 8(6):e64683. 2013.
Keyword : #HLA, #imputation, #ng
Xiaoming Jia, Buhm Han, Suna Onengut-Gumuscu, Wei-Min Chen, Patrick J. Concannon, Stephen S. Rich, Soumya Raychaudhuri, Paul I.W. de Bakker. “ Imputing Amino Acid Polymorphisms in Human Leukocyte Antigenes. ” PLoS One. 8(6):e64683. 2013.
Keyword : #HLA, #imputation, #ng